Time-domain near-infrared spectroscopy

Definition: Time-domain near-infrared spectroscopy, in the context of fNIRS, refers to measuring the distribution of photon times of flight through tissue and fitting the resulting histogram to a theoretical model to calculate tissue optical properties, including absorption and scattering coefficients. TD-NIRS, and its Fourier domain analogue swept frequency NIRS, permits gathering a richer data set than either single frequency-frequency domain NIRS or continuous wave NIRS. However, the cost of TD-NIRS hardware per detection channel tends to be higher.

Category: Physics

Related terms: temporal point spread function, diffuse time of flight curve, absorption coefficient, scattering coefficient

Abbreviation or symbol: TD fNIRS

Synonym: Time-resolved fNIRS

References:

https://doi.org/10.1088/0031-9155/42/5/007

http://dx.doi.org/10.1016/j.neuroimage.2013.05.106

https://doi.org/10.1117/12.2578518

https://doi.org/10.1364/boe.396585

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