Avalanche Photodiode

Definition: Avalanche photodiodes utilize the avalanche multiplication process to achieve higher electric output. The avalanche photodiode resembles a PIN photodiode except for the insertion of an additional p-type multiplying region. Most of the incident photons are absorbed in the intrinsic (‘I’) region and electron-hole pairs are first generated in this region as in the PIN photodiode. The holes drift toward the p-type region (‘P’) and the electrons toward the n-type (‘N’). The electrons, before reaching the n-type region, pass through a p-type multiplying region. If the electrons have undergone sufficient acceleration on reaching the multiplying region, new electron-hole pairs are generated by the collision- ionization process. The newly generated electron-hole pairs themselves generate more electron-hole pairs. The drawbacks to avalanche photodiodes are the high bias voltage needed, and the temperature compensation necessary for stable operation.

Category: Hardware

Related terms: Photomultiplier tube, Detector, Sensor, Silicon Photomultiplier

Abbreviation or symbol: APD

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References: E. Hui Pan. Fiber Optics Weekly Update. Information Gatekeepers Inc.

Alternative definition: An avalanche photodiode (APD) is a type of semiconductor photodetector used to detect low levels of light in applications such as fNIRS. It is based on the principle of avalanche multiplication, which occurs when an electron in the photodiode collides with an atom and generates a cascade of secondary electrons, resulting in a much larger current than would be caused by a single photon.

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Optode

Definition: An optode is the distal end of an fNIRS system which interfaces with the surface of the tissue being measured. Optodes can contain a single source (source optode), a single detector (detector optode), or a source accompanied by a short-separation detector.

Category: Hardware

Related terms: source; detector; emitter; emission, receiver, transmitter

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References: https://doi.org/10.1016/j.neuroimage.2005.08.008

https://biomedical.njit.edu/sites/biomedical/files/fNIRS%20Optode%20Helmet%20Construct.pdf

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Optode array

Definition: Relative arrangement of linked sources and detectors on a region of interest.

Category: Hardware

Related terms: Probe design; Optode placement, topographic layout, Montage

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Synonym: Probe array; fNIRS array; Channel configuration; fNIRS-sensor configuration; Source–detector array, fNIRS Montage

References: https://doi.org/10.1117/1.NPh.5.3.035010

https://doi.org/10.1117/1.NPh.8.1.012101

Alternative definition: A schematic arrangement of sources and detectors to create a pattern of measurement channels.

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References (alternative definition): https://doi.org/10.1117/1.NPh.8.1.012101  

Power supply

Definition: Power supply is an electronic device that provides a stable voltage, current, and frequency required for other devices to function correctly. This device maintains a stable rated wattage output consistently.

Category: Hardware

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References: https://doi.org/10.1109/TPEL.2019.2941528

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Probe

Definition: A probe or probeset is the arrangement of optodes on the head. Probes can be placed according to the international 10-20 system and/or other anatomical landmarks. The optodes (emitters and detectors) are typically located in a grid with fixed inter-optode-distances for long-distance and short-distance channels.

Category: Hardware

Related terms: topographic layout, optode placement, fNIRS caps, inter-optode-distance

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Synonym: probeset

References: –

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Related terms (alternative definition): Optode, Sensor, Detector, Source

References (alternative definition): https://dictionary.cambridge.org/dictionary/english-german/probe  

Sampling frequency

Definition: The number of samples per second collected from a continuous signal through analog-to-digital conversion.

Category: Hardware

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Synonym: Sampling Rate

References: https://doi.org/10.3389/fpsyg.2017.00093

Alternative definition: Number of data samples collected per unit of time (in Hz) from each channel.

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References (alternative definition): https://doi.org/10.1117/1.NPh.8.1.012101  

Saturation

Definition: In terms of a photodiode, if the incident optical power continues to increase but the photocurrent output stops growing, it indicates that the photodiode has reached saturation. The saturation limit can be adjusted by reducing the resistance seen by the load or changing the reverse bias voltage applied. The saturation point represents the upper boundary of the photodiode’s linear range, while the lower boundary of that linear range is determined by the noise. Beyond this range, the photodiode operates in a nonlinear manner.

Category: Hardware

Related terms: Photodiode

Abbreviation or symbol: Psat

Synonym: photocurrent output limit

References: https://doi.org/10.1364/OE.422478

https://www.thorlabs.com/images/TabImages/Photodetector_Lab.pdf

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Source-detector separation

Definition: Source-detector separation (SDS) refers to the physical distance between each fNIRS source-detector pair of optodes. It determines the signal-to-noise ratio (SNR), the number of measurable photons, depth sensitivity to the change in hemoglobin, the allowed amount of sources/detectors/channels, and the size of covered regions. Depending on the population being studied (e.g., adults vs. infants) and the purpose of the channels (e.g., measuring oxygenated hemoglobin in the brain vs. removing the confounding effects of superficial tissue physiology), the optimal SDS will vary. In a reflection geometry, larger SDS increases depth sensitivity (i.e., to deep regions further from the surface), at the cost of reduced total detected intensity.

Category: Hardware

Related terms: short-channel separation, source-detector pair

Abbreviation or symbol: SDS

Synonym: Source-detector separation range, Source-detector separation, inter-optode distance

References: https://doi.org/10.1117/1.NPh.2.2.025005

https://doi.org/10.1111/cpf.12156

https://doi.org/10.1117/1.JBO.21.9.091307

Alternative definition: The inter-optode distance is the spatial distance between a source and a detector. In circular geometries it is defined as the length of the chord between the optodes.

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References (alternative definition): https://doi.org/10.1007/978-1-4615-3404-4_17  

Artifact

Definition: In the context of fNIRS, an artifact is a disturbance of the fNIRS signal that makes the identification of physiologically relevant information in the fNIRS signal difficult or impossible. Generally it is a component of the fNIRS signal that is not induced by neuronal activity and may thus contaminate the measured hemodynamic response. Common sources of artifact in fNIRS data include relative movement between the optodes and the scalp (i.e. motion artifacts), optical signal changes caused by non-brain function related physiological variations (e.g., effects of blood flow changes in the scalp or respiration), environmental variations (e.g., due to stray or ambient light), as well as undesired instrument fluctuations (i.e., related to the measurement equipment).

Category: Analysis

Related terms: Physiological Noise, Filtering, Noise, Motion Correction, Accelerometer, Gyroscope, Inertial measurement Unit (IMU), Low-Pass Filter, High-Pass Filter, Band Pass Filter, baseline shift, baseline drift

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References:

https://doi.org/10.3389/fnins.2012.00147

https://doi.org/10.1016/j.neuroimage.2013.04.082

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Band-pass filtering

Definition: A band-pass filter is a combination of a low-pass and a high-pass filter and has the effect of attenuating frequencies above and below the passband frequencies. In the context of fNIRS, band-pass filtering is used as a signal processing step to reduce undesired fNIRS signal frequency components that are irrelevant to the brain functions of interest, i.e. task or stimulus evoked hemodynamic responses or resting-state hemodynamics.

Category: Analysis

Related terms: high-pass filtering, low-pass filtering, wavelet, temporal filtering

Abbreviation or symbol: bpf

Synonym: filtering

References:

https://doi.org/10.3389/fnhum.2019.00331

https://doi.org/10.1542/peds.2015-2326

http://dx.doi.org/10.1136/adc.76.2.151

https://doi.org/10.3389/fnhum.2013.00864

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