Large Concentration values
I wanted to see if anyone else has this experience. The range of values in my raw data seems acceptable and is even similar to values a colleague has gotten in their own data collection. However, when I convert OD to concentration, the concentration values are really high. I attached a pdf with screenshots of the raw data, concentration, and processing stream for reference. The screenshot is one of the more extreme examples but in general, my concentration values seem high compared to the literature.
Any thoughts or advice are greatly appreciated.
I'm curious to know if you've made any strides on this. I've been wracking my head over a similar situation as yours. To take it a step further, we've noticed large variabilities in the HRF amplitudes at the subject-level, which will influence our analysis/results at the group-level.